Stem Cells in Burn Eschar

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Stem cells in burn eschar.

This study compares mesenchymal cells isolated from excised burn wound eschar with adipose-derived stem cells (ASCs) and dermal fibroblasts in their ability to conform to the requirements for multipotent mesenchymal stem cells (MSCs). A population of multipotent stem cells in burn eschar could be an interesting resource for tissue engineering approaches to heal burn wounds. Cells from burn esc...

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Accumulative eschar after burn

Eschar formation is a potential sequela of burn injuries. Definitive management may include escharectomy and eschar debridement. After eschar removal, the wound can be covered with a skin graft or reepithelialization. For prolonged refractory eschar on the fingertips, topical use of rb-bFGF after debridement can achieve an optimal outcome.

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Burn injuries are a common and highly lethal trauma causing immense pain, suffering, disability, and unfortunately death. The secondary contracture can lead to loss of function and furthermore lifelong disability both physically and mentally. Stem cells have been used in a variety of clinical applications to repair and regenerate chronic wounds. However the use of stem cells in burns has just r...

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ژورنال

عنوان ژورنال: Cell Transplantation

سال: 2012

ISSN: 0963-6897,1555-3892

DOI: 10.3727/096368911x600993